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Lip SCC — SCE Dermatology MCQ

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HardSkin CancerLip SCCSCE Dermatology

A temple cutaneous squamous cell carcinoma is associated with facial numbness in the distribution of the trigeminal nerve. Histology shows perineural invasion. Which investigation best maps the clinically significant spread?

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Correct answer: CContrast-enhanced MRI along the involved nerve

Neurological symptoms with histological perineural invasion imply clinical perineural spread. Contrast-enhanced MRI is the preferred modality for assessing proximal extension along named nerves towards the skull base and informs specialist multidisciplinary surgery and radiotherapy planning.

Reference: https://academic.oup.com/bjd/pages/bad-guidelines