Basal Cell Carcinoma — SCE Dermatology MCQ
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Correct answer: B — Infiltrative/morphoeic
Infiltrative/morphoeic basal cell carcinoma is the high-risk subtype described by thin, irregular strands or spiky nests of basaloid tumour infiltrating a dense fibrotic or sclerotic stroma. This growth pattern produces poorly defined clinical and histological margins with subclinical extension, so standard excision has a higher risk of incomplete clearance and recurrence than well-circumscribed nodular, superficial or pigmented BCC. Basosquamous BCC is also regarded as aggressive, but the histology in the stem is classic for infiltrative/morphoeic BCC, which is the best answer.
Reference: British Association of Dermatologists. Guidelines for the management of adults with basal cell carcinoma, 2021. https://academic.oup.com/bjd/article/185/5/899/6599942