Oral Lichen Planus — SCE Dermatology MCQ

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ModerateInflammatory DermatosesOral Lichen PlanusSCE Dermatology

A 65-year-old man with oral squamous cell carcinoma asks about the relationship between oral lichen planus and malignancy. What is the WHO classification of oral LP regarding malignant potential?

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Correct answer: D — Oral LP is classified as a potentially malignant disorder by WHO

The WHO classifies oral lichen planus as a 'potentially malignant disorder', recognising its association with increased risk of oral squamous cell carcinoma. The estimated malignant transformation rate is approximately 0.5-1% per year, with erosive/atrophic forms carrying higher risk than reticular/plaque types. This necessitates long-term surveillance with regular oral examination and biopsy of any persistent ulceration, thickening, or morphological change. Risk factors for malignant transformation include hepatitis C infection, erosive subtype, tongue involvement, and tobacco/alcohol use. Management of OLP includes regular monitoring, topical corticosteroids, and addressing modifiable risk factors.

Reference: BAD 2019 LP Guidelines; WHO 2017 Oral Cancer