skip to main content

HIV Dermatology — SCE Dermatology MCQ

Instant feedback + full explanation. One question, done properly.

ModerateCutaneous InfectionHIV DermatologySCE Dermatology

A 40-year-old HIV-positive man (CD4 50 cells/μL) presents with extensive crusted papillomatous warts and severe molluscum contagiosum on his face. These infections are unusually widespread and treatment-resistant. What is the most important management priority?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: A — Initiation of antiretroviral therapy (ART) for immune reconstitution

In advanced HIV/AIDS, opportunistic cutaneous infections (extensive warts, giant molluscum, disseminated fungal infections, severe HSV, KS) reflect profound immune deficiency. The most important management priority is initiation of effective antiretroviral therapy (ART) to restore immune function. Immune reconstitution with rising CD4 count leads to spontaneous improvement or resolution of many HIV-associated dermatoses. Local treatment of individual lesions is supportive but ineffective long-term without addressing the underlying immunodeficiency. Immune reconstitution inflammatory syndrome (IRIS) may temporarily worsen some conditions after ART initiation.

Reference: BHIVA 2021 HIV Treatment Guidelines; BAD