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Seborrhoeic Keratosis — SCE Dermatology MCQ

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HardSkin CancerSeborrhoeic KeratosisSCE Dermatology

A heavily pigmented lesion has comedo-like openings but also marked asymmetry, irregular streaks and a blue-white veil. What is the safest management?

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Correct answer: D — Complete excision biopsy for histological diagnosis

Seborrhoeic keratosis features do not override melanoma-specific asymmetry and structures; collision lesions and melanomas mimicking keratosis occur. When dermoscopy remains suspicious, histological assessment by an appropriate biopsy is required before destructive treatment.

Reference: https://www.nice.org.uk/guidance/ng14/chapter/recommendations