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Psoriasis — SCE Dermatology MCQ

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EasyInflammatory DermatosesPsoriasisSCE Dermatology

A 48-year-old man with chronic plaque psoriasis has developed metabolic syndrome. His dermatologist explains that psoriasis is now recognised as more than just a skin disease. Which comorbidities are specifically associated with psoriasis according to BAD guidelines?

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Correct answer: E — Cardiovascular disease, metabolic syndrome (diabetes, obesity, dyslipidaemia), psoriatic arthritis, depression, and NAFLD

Psoriasis is recognised as a systemic inflammatory disease with multiple comorbidities. BAD guidelines identify key associations: cardiovascular disease (independent risk factor for MI/stroke), metabolic syndrome (diabetes, obesity, dyslipidaemia, hypertension), psoriatic arthritis (affects up to 30%), depression/anxiety (prevalence 2-3× higher), NAFLD, inflammatory bowel disease, and lymphoma. Holistic management requires screening for and addressing comorbidities alongside skin disease. Cardiovascular risk assessment (QRISK3), metabolic screening, and psoriatic arthritis assessment are recommended at baseline and periodically. Some biologic therapies may have beneficial cardiovascular effects.

Reference: BAD 2020 Psoriasis Comorbidities; NICE CG153