Atopic Eczema — SCE Dermatology MCQ
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Correct answer: B — Tacrolimus can cause facial flushing and erythema when alcohol is consumed (alcohol intolerance)
The best answer is “Tacrolimus can cause facial flushing and erythema when alcohol is consumed (alcohol intolerance)”. Eczema treatment is selected by site and severity, with topical corticosteroid or calcineurin-inhibitor safety, infection, adherence, contact allergy and psychosocial effects considered before escalation. The alternatives “Alcohol is absolutely contraindicated, when the full phenotype supports it, within an appropriate UK pathway”, “Alcohol reduces Tacrolimus efficacy, within an appropriate UK pathway, after clinicopathological correlation”, “Alcohol causes Tacrolimus toxicity, after clinicopathological correlation, after specialist assessment, when the full phenotype supports it”, “No interaction with alcohol, after specialist assessment, when the full phenotype supports it” are clinically adjacent possibilities, but they do not fit the defining morphology, distribution, histopathology, risk signal or management sequence in this stem.
Reference: NICE CG57 atopic eczema recommendations: https://www.nice.org.uk/guidance/cg57/chapter/Recommendations