Anogenital Warts — SCE Dermatology MCQ

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HardGenital DermatologyAnogenital WartsSCE Dermatology

A 20-year-old man presents with firm skin-coloured papules on his penis and perianal area. They are exophytic with a cauliflower-like surface. He has no other symptoms. What is the most common causative HPV subtype?

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Correct answer: E — HPV 6 and 11

The best answer is “HPV 6 and 11”. Genital lichen sclerosus causes pruritic porcelain-white atrophy and architectural change; persistent focal thickening, erosion, ulceration or tenderness requires assessment for differentiated VIN or squamous carcinoma. The alternatives “HPV 31 and 33”, “HPV 2 and 4”, “HPV 16 and 18”, “HPV 1” are clinically adjacent possibilities, but they do not fit the defining morphology, distribution, histopathology, risk signal or management sequence in this stem.

Reference: BAD lichen sclerosus information: https://www.bad.org.uk/pils/lichen-sclerosus-in-females