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Isotretinoin PPP — SCE Dermatology MCQ

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HardDermatopharmacologyIsotretinoin PPPSCE Dermatology

A patient who can become pregnant is starting oral isotretinoin in 2026. Which UK safety package is required?

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Correct answer: C — The MHRA Pregnancy Prevention Programme plus risk acknowledgement and mental-health and sexual-function monitoring

The UK uses the MHRA Pregnancy Prevention Programme for patients who can become pregnant, supported by pregnancy testing and effective contraception according to individual risk. All patients complete updated risk acknowledgement and receive monitoring for mental-health and sexual-function adverse effects. The blanket second-prescriber requirement for under-18s was removed in 2026.

Reference: https://www.gov.uk/drug-safety-update/isotretinoin-changes-to-prescribing-guidance-and-additional-risk-minimisation-measures