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Melanoma LVI — SCE Dermatology MCQ

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HardSkin CancerMelanoma LVISCE Dermatology

A resected primary melanoma is stage IIC. Which molecular testing approach is recommended under current NICE guidance?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: DCarry out BRAF analysis of the melanoma tissue

NICE recommends BRAF analysis for stage IIB to IV primary melanoma and consideration at stage IIA. Knowing BRAF status can expedite decisions about adjuvant trials or treatment at relapse; testing is performed on tumour tissue rather than as a germline blood test.

Reference: https://www.nice.org.uk/guidance/ng14/chapter/recommendations