Melanoma Microsatellites — SCE Dermatology MCQ

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HardSkin CancerMelanoma MicrosatellitesSCE Dermatology

A melanoma specimen contains microsatellites. Sentinel-node biopsy finds no nodal metastasis. What is the AJCC 8 nodal category?

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Correct answer: B — N1c

Microsatellite, satellite or in-transit metastasis without a tumour-involved regional node is N1c in AJCC 8. It becomes N2c when one regional node is involved and N3c when two or more are involved. Therefore microsatellites cannot be assigned N2c without stating nodal involvement.

Reference: https://www.nice.org.uk/guidance/ng14