A woman with pemphigoid gestationis asks about implications for her baby. Her disease began at 30 weeks with periumbilical urticarial plaques and

Question

A woman with pemphigoid gestationis asks about implications for her baby. Her disease began at 30 weeks with periumbilical urticarial plaques and linear C3 at the basement membrane zone. Which counselling statement is most accurate?

Accepted Answer

Transient antibody-mediated neonatal blistering can occur, with increased prematurity and fetal-growth-restriction risk

Answer

Neonatal blistering is inevitable whenever maternal direct immunofluorescence remains positive at delivery

Answer

Maternal disease predicts fetal pemphigoid that usually requires prolonged neonatal immunosuppression

Answer

The pregnancy has no fetal or neonatal association once maternal blistering is adequately controlled

Answer

The principal fetal risk is congenital scarring because BP180 antibodies permanently disrupt epidermal development

Pemphigoid Gestationis — SCE Dermatology MCQ

A woman with pemphigoid gestationis asks about implications for her baby. Her disease began at 30 weeks with periumbilical urticarial plaques and linear C3 at the basement membrane zone. Which counselling statement is most accurate?