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Cutaneous Lupus Erythematosus — SCE Dermatology MCQ

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ModerateDermatopharmacologyCutaneous Lupus ErythematosusSCE Dermatology

A 50-year-old woman is on long-term Hydroxychloroquine 200 mg twice daily for cutaneous lupus erythematosus. According to guidelines, what ophthalmological monitoring is recommended?

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Correct answer: C — Baseline and annual screening with optical coherence tomography (OCT) after 5 years of use

The Royal College of Ophthalmologists (RCOph) 2020 guidelines recommend baseline ophthalmic assessment within the first year of starting Hydroxychloroquine and annual screening from 5 years of use. Screening should include spectral domain OCT and automated visual field testing (10-2). Risk of retinal toxicity increases after 5 years of use and with cumulative dose. The maximum recommended dose is ≤5 mg/kg/day of actual body weight to reduce retinopathy risk.

Reference: RCOph 2020 Hydroxychloroquine and Chloroquine Retinopathy Screening Guideline