skip to main content

Erythema Multiforme — SCE Dermatology MCQ

Instant feedback + full explanation. One question, done properly.

HardDrug ReactionsErythema MultiformeSCE Dermatology

A patient has six episodes each year of acral true-target lesions appearing after herpes labialis. Episodes remain mucocutaneous erythema multiforme without epidermal detachment. Which preventive strategy is most appropriate?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: A — Offer twice-daily aciclovir for several months as continuous antiviral prophylaxis

A is correct. Frequent erythema multiforme consistently following herpes labialis is an indication to consider suppressive antiviral treatment, commonly low-dose aciclovir twice daily for several months. Treating only after the immune eruption is established may be too late to prevent that episode. Long-term corticosteroid creates substantial toxicity and does not suppress HSV, while antibacterial treatment has no role. Refractory recurrent EM may need specialist alternatives, but confirmation of morphology, trigger and adherence precedes immunomodulatory escalation. New widespread detachment or severe mucosal disease would require urgent reassessment for a different diagnosis.

Reference: British Association of Dermatologists: erythema multiforme: https://www.bad.org.uk/pils/erythema-multiforme