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Dermatomyositis — SCE Dermatology MCQ

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HardConnective Tissue & VasculitisDermatomyositisSCE Dermatology

An adult with new dermatomyositis has anti-TIF1-gamma antibodies, dysphagia and marked weight loss. Which management principle is most appropriate?

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Correct answer: EUndertake enhanced malignancy screening alongside routine assessment

Anti-TIF1-gamma, older age, dysphagia and systemic weight loss define a high malignancy-risk dermatomyositis phenotype. Screening should combine age- and sex-appropriate programmes with enhanced investigation guided by risk and specialist protocols, while treating the inflammatory disease.

Reference: https://academic.oup.com/bjd/pages/bad-guidelines