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Pemphigus Vulgaris — SCE Dermatology MCQ

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HardBlistering DiseasesPemphigus VulgarisSCE Dermatology

An older patient develops relatively non-inflammatory tense bullae after a new diabetes treatment. Biopsy confirms bullous pemphigoid. Which medication class has the strongest recognised association with this presentation?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: C — Dipeptidyl peptidase-4 inhibitors

Dipeptidyl peptidase-4 inhibitors, particularly some gliptins, are associated with bullous pemphigoid and may produce a less inflammatory phenotype. Medication review is therefore an important part of assessment, although treatment decisions should consider diabetic control and disease severity.

Reference: https://academic.oup.com/bjd/pages/bad-guidelines