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SLE Treatment Targets EULAR — SCE Rheumatology MCQ

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HardSLE & Antiphospholipid SyndromeSLE Treatment Targets EULARSCE Rheumatology

What is the preferred treat-to-target objective for systemic lupus erythematosus in current specialist recommendations?

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Correct answer: A — Target remission or an accepted low-disease-activity state

The best answer is “Target remission or an accepted low-disease-activity state”. Current lupus management aims for remission, with low disease activity an acceptable alternative when remission is not achievable, while preventing flares and minimizing glucocorticoid exposure. Serology alone is insufficient, DAS28 is a rheumatoid instrument, chronic glucocorticoids are not the target, and a measurement schedule is not itself a clinical outcome.

Reference: EULAR systemic lupus erythematosus management recommendations: https://ard.bmj.com/content/83/1/15