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Biologic Interval Extension — SCE Rheumatology MCQ

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ModerateRheumatoid ArthritisBiologic Interval ExtensionSCE Rheumatology

A 48-year-old woman on Adalimumab and MTX in remission 2 years. Her rheumatologist extends Adalimumab interval. What evidence?

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Correct answer: C — STRASS and other trials support dose reduction in sustained remission; 60-80% maintain LDA; retreatment effective after flare

STRASS DRESS POET: biologic tapering in sustained remission. 60-80% maintain LDA. Retreatment >90% effective. Gradual preferred over abrupt.

Reference: EULAR 2022; Fautrel B 2015