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SLE Retinal Vasculitis — SCE Rheumatology MCQ

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ModerateRheumatology EmergenciesSLE Retinal VasculitisSCE Rheumatology

A 45-year-old woman with SLE develops acute visual loss. Fundoscopy shows cotton-wool spots and retinal vasculitis. What immediate treatment is needed?

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Correct answer: A — High-dose IV Methylprednisolone (1g daily for 3 days) and urgent ophthalmological co-management as SLE retinal vasculitis can cause permanent visual loss

SLE retinal vasculitis: sight-threatening emergency. Cotton-wool spots retinal haemorrhages and vascular occlusion. Urgent IV Methylprednisolone plus immunosuppression intensification (Cyclophosphamide or Rituximab). Ophthalmology co-management essential. May need intravitreal therapy.

Reference: EULAR 2023 SLE; NPSLE guidance