skip to main content

Steroid Dose Equivalences — SCE Rheumatology MCQ

Instant feedback + full explanation. One question, done properly.

EasyRheumatology PharmacologySteroid Dose EquivalencesSCE Rheumatology

A 50-year-old woman with RA asks about Prednisolone dosing equivalences. What is the approximate anti-inflammatory equivalence between Prednisolone and Methylprednisolone?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: A — Methylprednisolone has approximately 25% greater anti-inflammatory potency than Prednisolone; 4mg Methylprednisolone is approximately equivalent to 5mg Prednisolone

Glucocorticoid equivalences: Prednisolone 5mg = Methylprednisolone 4mg = Hydrocortisone 20mg = Dexamethasone 0.75mg. Methylprednisolone has minimal mineralocorticoid activity. These equivalences are important for dose conversions between routes and preparations.

Reference: BNF corticosteroid equivalences