skip to main content

DORIS Remission Definition — SCE Rheumatology MCQ

Instant feedback + full explanation. One question, done properly.

HardSLE & Antiphospholipid SyndromeDORIS Remission DefinitionSCE Rheumatology

A woman with systemic lupus erythematosus has clinical SLEDAI-2K of 0, physician global assessment below 0.5 and prednisolone 5 mg daily. She continues stable hydroxychloroquine and azathioprine. How does the 2021 DORIS definition classify this state?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: B — Classify remission on treatment because DORIS thresholds are met

The best answer is “Classify remission on treatment because DORIS thresholds are met”. The 2021 DORIS definition uses clinical SLEDAI-2K of 0, physician global assessment below 0.5 and prednisolone no more than 5 mg daily; stable antimalarial, immunosuppressive or biologic treatment is permitted. Complete drug withdrawal and normalized serology are not required, and the definition itself does not impose a twelve-month duration.

Reference: 2021 DORIS remission definition: https://ard.bmj.com/content/80/2/181