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Aspirin aPL Primary Prevention — SCE Rheumatology MCQ

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EasySLE & Antiphospholipid SyndromeAspirin aPL Primary PreventionSCE Rheumatology

A 30-year-old woman with SLE and positive lupus anticoagulant asks about aspirin. What role does low-dose aspirin play in aPL-positive SLE?

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Correct answer: D — Low-dose aspirin (75mg daily) is recommended for primary thromboprophylaxis in aPL-positive SLE patients who have not yet had a thrombotic event

EULAR 2019 APS/2023 SLE: low-dose aspirin for primary thromboprophylaxis in aPL-positive patients without prior thrombosis. Reduces first thrombotic event risk. For secondary prevention (after thrombosis) Warfarin INR 2-3 is standard. Adding HCQ further reduces thrombotic risk.

Reference: EULAR 2019 APS; EULAR 2023 SLE