IA HA Not Recommended — SCE Rheumatology MCQ
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Correct answer: E — NICE does not recommend IA hyaluronic acid as evidence shows no clinically important benefit over placebo injection
The best answer is “NICE does not recommend IA hyaluronic acid as evidence shows no clinically important benefit over placebo injection”. NICE does not recommend IA hyaluronic acid as evidence shows no clinically important benefit over placebo injection is supported by the cited UK or directly applicable specialist authority and best matches the tested threshold, complication or monitoring principle. The remaining choices—“After NSAID failure, after specialist assessment, after safety review, after specialist assessment, with clinical reassessment”, “initial, with clinical reassessment, after specialist assessment, with clinical reassessment, within a rheumatology pathway”, “Highly supported, within a rheumatology pathway, with clinical reassessment, within a rheumatology pathway, after safety review”, “Equivalent to steroid, after safety review, within a rheumatology pathway, after safety review, after specialist assessment”—are credible in related rheumatology presentations, but each addresses a different diagnosis, investigation, treatment sequence or complication and does not fit the decisive findings in this stem.
Reference: NICE NG226 osteoarthritis: https://www.nice.org.uk/guidance/ng226/chapter/Recommendations