MMF Dosing LN Induction — SCE Rheumatology MCQ

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ModerateSLE & Antiphospholipid SyndromeMMF Dosing LN InductionSCE Rheumatology

A 35-year-old woman with class IV LN starts Mycophenolate. What is the EULAR 2023 target induction dose?

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Correct answer: C — MMF 2-3 g/day titrated over 2-4 weeks

EULAR 2023: MMF 2-3g/day started at 500mg BD titrated to 1-1.5g BD. ALMS trial established non-inferiority to CYC. MMF now preferred first-line for most class III/IV/V LN.

Reference: EULAR 2023 SLE; Appel GB et al 2009 ALMS