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Foot Examination in Early RA — SCE Rheumatology MCQ

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HardMusculoskeletal ImagingFoot Examination in Early RASCE Rheumatology

A patient with primary Sjögren syndrome has severe xerostomia and keratoconjunctivitis sicca despite topical measures. Pilocarpine is tolerated. Which trial regimen and stopping review match the UK SmPC?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: E — Use 5 mg at mealtimes and bedtime; stop after 2–3 months if ineffective

Explanation lettering: B = shown as A · A = shown as B · E = shown as D · D = shown as E

D is correct. Sjögren symptoms are treated with pilocarpine 5 mg four times daily, at mealtimes and bedtime; a tolerated dose may be increased to a maximum 30 mg daily. Treatment is discontinued when neither dry-mouth nor dry-eye symptoms improve after two to three months. The 5 mg three-times-daily starting schedule belongs to post-radiotherapy xerostomia.

Reference: Salagen 5 mg film-coated tablets SmPC: https://www.medicines.org.uk/emc/product/1370/smpc