SDI Organ Domains — SCE Rheumatology MCQ
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Correct answer: B — Ocular; neuropsychiatric; renal; pulmonary; cardiovascular; peripheral vascular; gastrointestinal; musculoskeletal; skin; premature gonadal failure; diabetes; malignancy
The SDI assesses accumulated damage across 12 domains: ocular, neuropsychiatric, renal, pulmonary, cardiovascular, peripheral vascular, gastrointestinal, musculoskeletal, skin, premature gonadal failure, diabetes and malignancy. Damage is recorded after the onset of SLE and irrespective of whether it resulted from lupus activity, treatment or another process, provided the relevant SDI definition is met. Haematological and immunological abnormalities are important in SLE activity and classification instruments but are not separate SDI damage domains. Infection is not an independent domain, although its permanent consequences may satisfy individual damage items. Obstetric morbidity is central to antiphospholipid syndrome assessment but is not an SDI domain. The original item was rewritten because option B was conspicuously longer than implausible distractors, making the answer heavily cued.
Reference: Ryu S et al. Associates and predictors of pleurisy or pericarditis in SLE, Methods—organ damage domains, 2017. https://oml.eular.org/oml_search_results_details.cfm?action=All+information&id=345&lightbox%5Bheight%5D=90p&lightbox%5Biframe%5D=true&lightbox%5Bwidth%5D=90p