Live Vaccine Biologic Washout — SCE Rheumatology MCQ
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Correct answer: C — Avoid live vaccine during immunosuppression and coordinate travel planning
The best answer is “Avoid live vaccine during immunosuppression and coordinate travel planning”. Yellow-fever vaccine is live and can cause serious infection in immunosuppressed people. Timing depends on the medicine, immune recovery, destination risk and whether an exemption or itinerary change is safer, so an unqualified fixed interval should not be improvised. Same-day dosing, universal two-week or six-month rules and immediate restart are unsafe simplifications.
Reference: UK Green Book immunisation guidance: https://www.gov.uk/government/collections/immunisation-against-infectious-disease-the-green-book