Early RA Referral — SCE Rheumatology MCQ
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Correct answer: C — Refer urgently to rheumatology while investigations continue
Explanation lettering: E = shown as A · A = shown as D · D = shown as E
C is correct. NICE requires urgent specialist referral for persistent small-joint or polyarticular synovitis even when acute-phase markers, RF and anti-CCP are negative. Tests ordered in primary care must not delay referral. Ultrasound confirmation and repeat serology are unnecessary gatekeepers, while empirical long-term glucocorticoid can obscure assessment and create toxicity.
Reference: NICE NG100: rheumatoid arthritis recommendations. https://www.nice.org.uk/guidance/ng100/chapter/Recommendations