Teriparatide is being considered for severe osteoporosis in a patient taking digoxin for atrial fibrillation. Calcium is at the upper end of normal.

Question

Teriparatide is being considered for severe osteoporosis in a patient taking digoxin for atrial fibrillation. Calcium is at the upper end of normal. Which issue most directly requires caution?

Accepted Answer

Teriparatide can transiently raise calcium and thereby predispose to digitalis toxicity

Answer

Teriparatide induces P-glycoprotein and lowers digoxin exposure below its therapeutic range

Answer

Teriparatide suppresses calcium and increases digoxin-associated ventricular ectopy

Answer

Teriparatide inhibits renal tubular digoxin secretion and mandates a fixed 50% dose reduction

Answer

Teriparatide chelates digoxin in the intestine and requires six-hour dose separation

Draining Tophus — SCE Rheumatology MCQ

Teriparatide is being considered for severe osteoporosis in a patient taking digoxin for atrial fibrillation. Calcium is at the upper end of normal. Which issue most directly requires caution?