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ASDAS Scoring — SCE Rheumatology MCQ

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EasySpondyloarthropathyASDAS ScoringSCE Rheumatology

A 32-year-old man with axial spondyloarthritis has an ASDAS-CRP score of 1.8. Using the current ASDAS disease-activity state nomenclature, how should this score be classified?

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Correct answer: CLow disease activity

The correct answer is C, low disease activity. Current ASDAS states are inactive disease below 1.3, low disease activity from 1.3 to below 2.1, high disease activity from 2.1 to 3.5, and very high disease activity above 3.5. An ASDAS-CRP of 1.8 therefore lies within the low-disease-activity interval. “Moderate disease activity” was the former name for this interval and was replaced by “low disease activity” in the updated ASDAS nomenclature. Inactive disease requires a score below 1.3, while high and very high disease activity require substantially higher scores.

Reference: Benavent D et al. Achievement rate and predictive factors of the recommended therapeutical target in patients with axial spondyloarthritis who remain on biological therapy: a prospective cohort study in Spain. BMJ Open. 2022;12:e057850. https://pubmed.ncbi.nlm.nih.gov/21068095/