RA Treat-to-Target — SCE Rheumatology MCQ

Instant feedback + full explanation. One question, done properly.

EasyRheumatoid ArthritisRA Treat-to-TargetSCE Rheumatology

A 50-year-old woman with RA has a DAS28-ESR of 3.8. She is on Methotrexate 25 mg weekly and Hydroxychloroquine. According to EULAR 2022 what is the treatment target in RA?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: C — DAS28 <3.2 (low disease activity) or <2.6 (remission)

EULAR 2022 recommends a treat-to-target strategy aiming for remission (DAS28 <2.6 or Boolean remission) as the primary target. If remission is not achievable low disease activity (DAS28 <3.2) is an acceptable alternative target. Treatment should be adjusted every 3 months until the target is reached. This patient with DAS28 3.8 (moderate disease activity) has not achieved target and treatment escalation should be considered (adding another csDMARD or switching to subcutaneous Methotrexate before biologic escalation).

Reference: EULAR 2022 - Recommendations for management of RA