UCTD — SCE Rheumatology MCQ

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HardAutoimmune SerologyUCTDSCE Rheumatology

A 35-year-old woman has a positive ANA at 1:320 with a speckled pattern. She has Raynaud phenomenon mild arthralgia and fatigue but does not meet criteria for any specific CTD. What is the most appropriate label for her condition?

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Correct answer: B — Undifferentiated connective tissue disease (UCTD)

The best answer is “Undifferentiated connective tissue disease (UCTD)”. Undifferentiated connective tissue disease (UCTD) is supported by the cited UK or directly applicable specialist authority and best matches the tested threshold, complication or monitoring principle. The remaining choices—“Mixed connective tissue disease”, “SLE, after safety review”, “Sjogren syndrome, after specialist assessment”, “Fibromyalgia, with clinical reassessment”—are credible in related rheumatology presentations, but each addresses a different diagnosis, investigation, treatment sequence or complication and does not fit the decisive findings in this stem.

Reference: BSR 2024 systemic sclerosis guideline: https://pmc.ncbi.nlm.nih.gov/articles/PMC11534099/