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Inclusion Body Myositis — SCE Rheumatology MCQ

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HardMyositisInclusion Body MyositisSCE Rheumatology

A patient with inclusion-body myositis has slowly progressive quadriceps and finger-flexor weakness plus dysphagia. Which management principle is best supported?

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Correct answer: CExercise, falls-prevention and swallowing programmes without routine immunosuppression

No immunosuppressive medicine has shown sustained functional benefit in inclusion-body myositis. Management therefore prioritises tailored exercise, mobility and falls interventions, orthotics, swallowing surveillance, nutrition and respiratory assessment.

Reference: NHS England 2025 clinical commissioning policy for therapeutic immunoglobulin (Updated 2025): https://www.england.nhs.uk/wp-content/uploads/2021/12/ccp-for-the-use-of-therapeutic-immunoglobulin-england-2025.pdf; Current review of inclusion-body myositis management (Published 2024): https://pmc.ncbi.nlm.nih.gov/articles/PMC11646336/