SLE — SCE Rheumatology MCQ
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Correct answer: B — Current lupus disease activity using weighted clinical and laboratory descriptors
The best answer is “Current lupus disease activity using weighted clinical and laboratory descriptors”. SLEDAI-2K measures current SLE disease activity through weighted manifestations across organ systems; accumulated irreversible damage and patient-reported impact are assessed with different instruments. The remaining choices—“Irreversible organ damage accumulated since diagnosis, after specialist assessment”, “Patient-reported fatigue, pain and dryness, with clinical reassessment”, “Cumulative glucocorticoid toxicity, after safety review, within a rheumatology pathway”, “Ten-year cardiovascular event risk, after safety review”—are credible in related rheumatology presentations, but each addresses a different diagnosis, investigation, treatment sequence or complication and does not fit the decisive findings in this stem.
Reference: EULAR recommendations for systemic lupus erythematosus: https://ard.bmj.com/content/83/1/15