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Gout — SCE Rheumatology MCQ

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HardCrystal ArthropathyGoutSCE Rheumatology

A patient has recurrent attacks of podagra but synovial fluid repeatedly shows calcium pyrophosphate crystals. Which long-term statement is correct?

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Correct answer: BUrate-lowering therapy does not treat CPP crystal deposition

CPP crystal deposition is distinct from monosodium-urate gout. Allopurinol and febuxostat lower urate but do not remove CPP crystals. Management addresses acute inflammation, recurrence and associated metabolic disorders such as hyperparathyroidism or haemochromatosis where clinically indicated.

Reference: https://www.nice.org.uk/guidance/conditions-and-diseases/musculoskeletal-conditions