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Takayasu Arteritis — SCE Rheumatology MCQ

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HardVasculitisTakayasu ArteritisSCE Rheumatology

A 72-year-old with severe osteoporosis had an ischaemic stroke seven years ago and now has no residual deficit. Which statement about romosozumab is correct in UK prescribing?

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Correct answer: DAny previous stroke contraindicates romosozumab in the UK SmPC

Explanation lettering: D = shown as A · C = shown as B · A = shown as C · B = shown as D

B is correct. The UK SmPC contraindicates romosozumab in patients with a history of myocardial infarction or stroke; it does not restrict that contraindication to events in the previous year. Aspirin co-treatment and dose reduction do not remove the labelled cardiovascular risk. This differs from looser wording sometimes encountered in secondary summaries.

Reference: Evenity 105 mg pre-filled pen SmPC: https://www.medicines.org.uk/emc/product/10956/smpc