Gout — SCE Rheumatology MCQ

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HardCrystal ArthropathyGoutSCE Rheumatology

A patient with severe tophaceous gout starts urate-lowering therapy. Which serum-urate target is reasonable once treatment is tolerated?

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Correct answer: D — Below 300 micromol/L

A lower serum-urate target below 300 micromol/L can be considered for tophi, chronic gouty arthritis or persistent frequent flares. The dose is titrated with prophylaxis and safety monitoring until crystal burden resolves and sustained control is achieved.

Reference: https://www.nice.org.uk/guidance/ng219