SLE — SCE Rheumatology MCQ

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EasySLE & Antiphospholipid SyndromeSLESCE Rheumatology

A 30-year-old woman with SLE achieves sustained remission on Mycophenolate and Prednisolone 7.5 mg daily. According to EULAR 2023, what is the maximum acceptable maintenance dose of Prednisolone?

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Correct answer: A — 5 mg/day

EULAR 2023 states glucocorticoids should be minimised to 5 mg/day prednisone equivalent or less for maintenance, and when possible, withdrawn entirely. Doses above 5 mg/day contribute to damage accrual. This represents a strengthening of the previous recommendation to minimise steroid exposure. Biologics (Belimumab, Anifrolumab) and immunosuppressives should be used to facilitate steroid tapering.

Reference: EULAR 2023 - Recommendations for the management of systemic lupus erythematosus