A woman with a history of organ transplant (kidney) on tacrolimus and mycophenolate requests contraception. Tacrolimus is not an enzyme inducer. What ...

Question

A woman with a history of organ transplant (kidney) on tacrolimus and mycophenolate requests contraception. Tacrolimus is not an enzyme inducer. What are the key considerations?

Accepted Answer

Mycophenolate is teratogenic - highly effective contraception is essential. Tacrolimus is not an enzyme inducer. CHC may increase tacrolimus levels (as oestrogen inhibits CYP3A4); monitoring may be needed. LARC is preferred for efficacy

Answer

Any method is suitable without concern

Answer

Only condoms are safe after organ transplant

Answer

Hormonal contraception interferes with transplant function

Answer

She must stop mycophenolate before using contraception

uk-dfsrh MCQ (SBA): Organ Transplant Tacrolimus Mycophenolate Contraception

A woman with a history of organ transplant (kidney) on tacrolimus and mycophenolate requests contraception. Tacrolimus is not an enzyme inducer. What are the key considerations?