A 26-year-old woman using a combined oral contraceptive pill (COC) has been prescribed a GLP-1 receptor agonist (semaglutide) for weight management. S...

Question

A 26-year-old woman using a combined oral contraceptive pill (COC) has been prescribed a GLP-1 receptor agonist (semaglutide) for weight management. She reports frequent nausea. What contraceptive consideration is important?

Accepted Answer

GLP-1 agonists can cause nausea, vomiting, and delayed gastric emptying, which may reduce the absorption of oral contraceptives; a non-oral method may be more reliable

Answer

No consideration is needed

Answer

Semaglutide is an enzyme inducer

Answer

She should take her COC at the same time as semaglutide to enhance absorption

Answer

GLP-1 agonists increase COC efficacy

uk-dfsrh MCQ (SBA): GLP-1 Agonist and Oral Contraception Absorption

A 26-year-old woman using a combined oral contraceptive pill (COC) has been prescribed a GLP-1 receptor agonist (semaglutide) for weight management. She reports frequent nausea. What contraceptive consideration is important?