A 45-year-old woman presents with symmetrical pain and swelling of the MCP and PIP joints for 4 months, prolonged morning stiffness and raised inflamm...

Question

A 45-year-old woman presents with symmetrical pain and swelling of the MCP and PIP joints for 4 months, prolonged morning stiffness and raised inflammatory markers. Rheumatoid factor and anti-CCP antibodies are positive. X-rays show no erosions. What is the most appropriate initial disease-modifying treatment strategy?

Accepted Answer

Start Methotrexate as a single DMARD with folic acid

Answer

Non-steroidal anti-inflammatory drugs alone

Answer

Delay DMARDs until erosions appear

Answer

Short course of oral steroids only

Answer

Start Hydroxychloroquine only and review in 1 year

uk-plab-1 MCQ (SBA): Rheumatoid arthritis