A 37-year-old woman with schizophrenia on depot antipsychotic presents with low mood, anhedonia, and early morning wakening for 2 months. She denies s...

Question

A 37-year-old woman with schizophrenia on depot antipsychotic presents with low mood, anhedonia, and early morning wakening for 2 months. She denies suicidality. There is no evidence of psychotic relapse. What is the most appropriate next step?

Accepted Answer

Consider starting an SSRI such as Sertraline alongside close monitoring

Answer

Increase the dose of depot antipsychotic only

Answer

Stop the depot and start a tricyclic antidepressant

Answer

Do nothing as her symptoms are expected in schizophrenia

Answer

Admit her under the Mental Health Act immediately

uk-plab-1 MCQ (SBA): Depression in schizophrenia

A 37-year-old woman with schizophrenia on depot antipsychotic presents with low mood, anhedonia, and early morning wakening for 2 months. She denies suicidality. There is no evidence of psychotic relapse. What is the most appropriate next step?