A 40-year-old man presents with a 3-month history of watery diarrhoea, abdominal pain and weight loss. He has no rectal bleeding. Blood tests show mic...

Question

A 40-year-old man presents with a 3-month history of watery diarrhoea, abdominal pain and weight loss. He has no rectal bleeding. Blood tests show microcytic anaemia and low ferritin. Coeliac serology shows positive tissue transglutaminase antibodies. What is the most appropriate next step?

Accepted Answer

Refer for upper GI endoscopy with duodenal biopsies

Answer

Start a gluten-free diet immediately without further investigation

Answer

Arrange colonoscopy to look for colitis

Answer

Treat with oral iron and review in 6 months

Answer

Order CT abdomen to exclude malignancy

uk-plab-1 MCQ (SBA): Coeliac disease

A 40-year-old man presents with a 3-month history of watery diarrhoea, abdominal pain and weight loss. He has no rectal bleeding. Blood tests show microcytic anaemia and low ferritin. Coeliac serology shows positive tissue transglutaminase antibodies. What is the most appropriate next step?