A 52-year-old woman has established rheumatoid arthritis with joint damage. She has active synovitis in several joints despite regular NSAIDs. Rheumat...

Question

A 52-year-old woman has established rheumatoid arthritis with joint damage. She has active synovitis in several joints despite regular NSAIDs. Rheumatoid factor and anti-CCP antibodies are positive. What is the most appropriate next step in disease-modifying treatment?

Accepted Answer

Commence Methotrexate with appropriate monitoring and folic acid supplementation

Answer

Start long-term high-dose Prednisolone

Answer

Start Allopurinol

Answer

Start Paracetamol alone for pain control

Answer

Begin physiotherapy alone with no drug treatment

uk-plab-1 MCQ (SBA): Rheumatoid arthritis – DMARD initiation

A 52-year-old woman has established rheumatoid arthritis with joint damage. She has active synovitis in several joints despite regular NSAIDs. Rheumatoid factor and anti-CCP antibodies are positive. What is the most appropriate next step in disease-modifying treatment?