A 55-year-old man on warfarin for atrial fibrillation presents with massive haematemesis and hypotension. His INR is 6.2. He is actively bleeding and ...

Question

A 55-year-old man on warfarin for atrial fibrillation presents with massive haematemesis and hypotension. His INR is 6.2. He is actively bleeding and requires urgent reversal of anticoagulation. Which is the most appropriate immediate strategy to reverse warfarin?

Accepted Answer

Give IV Vitamin K and four-factor prothrombin complex concentrate

Answer

Stop warfarin and observe only

Answer

Give oral Vitamin K alone

Answer

Give prophylactic-dose low molecular weight heparin

Answer

Give fresh frozen plasma alone

uk-plab-1 MCQ (SBA): Warfarin-associated major haemorrhage

A 55-year-old man on warfarin for atrial fibrillation presents with massive haematemesis and hypotension. His INR is 6.2. He is actively bleeding and requires urgent reversal of anticoagulation. Which is the most appropriate immediate strategy to reverse warfarin?