A 62-year-old man with a 40-pack-year smoking history presents with chronic cough and exertional breathlessness. Spirometry shows FEV₁/FVC ratio of 0....

Question

A 62-year-old man with a 40-pack-year smoking history presents with chronic cough and exertional breathlessness. Spirometry shows FEV₁/FVC ratio of 0.6 and FEV₁ 65% predicted. What is the most appropriate first-line pharmacological treatment according to NICE?

Accepted Answer

Short-acting beta₂ agonist (SABA) or short-acting muscarinic antagonist (SAMA) as required

Answer

Inhaled corticosteroid monotherapy

Answer

Long-acting beta₂ agonist plus inhaled corticosteroid

Answer

Long-acting muscarinic antagonist only

Answer

Oral Theophylline

uk-plab-1 MCQ (SBA): COPD initial pharmacotherapy

A 62-year-old man with a 40-pack-year smoking history presents with chronic cough and exertional breathlessness. Spirometry shows FEV₁/FVC ratio of 0.6 and FEV₁ 65% predicted. What is the most appropriate first-line pharmacological treatment according to NICE?