A 72-year-old man with osteoarthritis is admitted with vomiting and diarrhoea. He has been taking Ramipril and Ibuprofen regularly. His creatinine has...

Question

A 72-year-old man with osteoarthritis is admitted with vomiting and diarrhoea. He has been taking Ramipril and Ibuprofen regularly. His creatinine has risen from 90 µmol/L baseline to 220 µmol/L. He is clinically mildly dehydrated. What is the most appropriate initial management?

Accepted Answer

Stop Ramipril and Ibuprofen and give intravenous fluids

Answer

Continue Ramipril but stop Ibuprofen

Answer

Commence high-dose loop diuretics

Answer

Start renal replacement therapy immediately

Answer

No change in medications and review in 1 week

uk-plab-1 MCQ (SBA): Acute kidney injury

A 72-year-old man with osteoarthritis is admitted with vomiting and diarrhoea. He has been taking Ramipril and Ibuprofen regularly. His creatinine has risen from 90 µmol/L baseline to 220 µmol/L. He is clinically mildly dehydrated. What is the most appropriate initial management?