A 25-year-old man with sickle cell disease presents with severe generalised bone pain, particularly in his limbs, and is afebrile. There are no focal ...

Question

A 25-year-old man with sickle cell disease presents with severe generalised bone pain, particularly in his limbs, and is afebrile. There are no focal signs of infection. What is the most appropriate initial management?

Accepted Answer

Adequate opioid analgesia, hydration and oxygen as needed

Answer

Immediate exchange transfusion

Answer

Start hydroxycarbamide in the emergency department

Answer

Discharge with paracetamol only

Answer

Start high-dose steroids

uk-plab-1 MCQ (SBA): Sickle cell crisis

A 25-year-old man with sickle cell disease presents with severe generalised bone pain, particularly in his limbs, and is afebrile. There are no focal signs of infection. What is the most appropriate initial management?