A 74-year-old man with long-standing Parkinson’s disease presents with worsening bradykinesia and rigidity now interfering with activities of daily li...

Question

A 74-year-old man with long-standing Parkinson’s disease presents with worsening bradykinesia and rigidity now interfering with activities of daily living. He is currently on a low dose of Levodopa/Carbidopa. According to current guidance, what is the most appropriate next step?

Accepted Answer

Optimise Levodopa dose to best symptom control

Answer

Stop Levodopa and start a dopamine agonist only

Answer

Switch to anticholinergic monotherapy

Answer

Prescribe Haloperidol for rigidity

Answer

No pharmacological changes are required

uk-plab-1 MCQ (SBA): Parkinson’s disease – optimisation of therapy

A 74-year-old man with long-standing Parkinson’s disease presents with worsening bradykinesia and rigidity now interfering with activities of daily living. He is currently on a low dose of Levodopa/Carbidopa. According to current guidance, what is the most appropriate next step?