A 72-year-old woman on long-term Warfarin for atrial fibrillation presents with melaena and hypotension. Her INR is 5.6. She is actively bleeding and ...

Question

A 72-year-old woman on long-term Warfarin for atrial fibrillation presents with melaena and hypotension. Her INR is 5.6. She is actively bleeding and haemodynamically unstable. What is the most appropriate strategy to reverse anticoagulation?

Accepted Answer

Administer intravenous vitamin K and prothrombin complex concentrate

Answer

Stop Warfarin only and observe

Answer

Give subcutaneous vitamin K alone

Answer

Give fresh frozen plasma only

Answer

Switch from Warfarin to a direct oral anticoagulant

au-amc MCQ (SBA): Warfarin-associated major bleeding

A 72-year-old woman on long-term Warfarin for atrial fibrillation presents with melaena and hypotension. Her INR is 5.6. She is actively bleeding and haemodynamically unstable. What is the most appropriate strategy to reverse anticoagulation?